从VS2012开始，您可以只使用Blend名称空间IsHidden属性：

• 添加，如果还不存在xmlns：d=”http://schemas.microsoft.com/expression/blend/2008“
• 将d：IsHidden=“true”放在只想在设计时隐藏的元素上

好办法，我也遇到过类似的问题，我同意在某些情况下需要这样做。这里有一个小的更新，允许你在设计时编辑值来打开和关闭IsHidden。我还应用了ScaleTransform而不是设置宽度和高度，以减少屏幕伪像，如果控件夹等显示，并避免冲突，如果被隐藏的控件已经设置了宽度和高度属性（假设控件尚未设置LayoutTransform）。

Public Class DesignModeTool

  Public Shared ReadOnly IsHiddenProperty As DependencyProperty = DependencyProperty.RegisterAttached( _
    "IsHidden", GetType(Boolean), GetType(DesignModeTool), _
    New FrameworkPropertyMetadata(False, New PropertyChangedCallback(AddressOf OnIsHiddenChanged)))

  Public Shared Sub SetIsHidden(ByVal element As FrameworkElement, ByVal value As Boolean)
    element.SetValue(IsHiddenProperty, value)
  End Sub

  Public Shared Function GetIsHidden(ByVal element As FrameworkElement) As Boolean
    Return DirectCast(element.GetValue(IsHiddenProperty), Boolean)
  End Function

  Private Shared Sub OnIsHiddenChanged(ByVal d As DependencyObject, ByVal e As DependencyPropertyChangedEventArgs)
    If System.ComponentModel.DesignerProperties.GetIsInDesignMode(d) AndAlso True.Equals(e.NewValue) Then
      With DirectCast(d, FrameworkElement)
        .LayoutTransform = New ScaleTransform(0.001, 0.001)
      End With
    ElseIf System.ComponentModel.DesignerProperties.GetIsInDesignMode(d) AndAlso False.Equals(e.NewValue) Then
      With DirectCast(d, FrameworkElement)
        .LayoutTransform = Nothing
      End With
    End If
  End Sub
End Class

干得好！我把它翻译成了C#，并把它的属性改成了RenderTransform。

static class DesignModeTool
{
    public static readonly DependencyProperty IsHiddenProperty =
        DependencyProperty.RegisterAttached("IsHidden",
            typeof(bool),
            typeof(DesignModeTool),
            new FrameworkPropertyMetadata(false,
                new PropertyChangedCallback(OnIsHiddenChanged)));

    public static void SetIsHidden(FrameworkElement element, bool value)
    {
        element.SetValue(IsHiddenProperty, value);
    }

    public static bool GetIsHidden(FrameworkElement element)
    {
        return (bool)element.GetValue(IsHiddenProperty);
    }

    private static void OnIsHiddenChanged(DependencyObject d,
                                          DependencyPropertyChangedEventArgs e)
    {
        if (!DesignerProperties.GetIsInDesignMode(d)) return;
        var element = (FrameworkElement)d;
        element.RenderTransform = (bool)e.NewValue
           ? new ScaleTransform(0, 0)
           : null;
    }
}

由于没有内置的方法来实现这一点，我决定自己实现一个解决方案，使用附加属性可以非常容易地做到这一点：

Public Class DesignModeTool
    Public Shared ReadOnly IsHiddenProperty As DependencyProperty = DependencyProperty.RegisterAttached( _
        "IsHidden", GetType(Boolean), GetType(DesignModeTool), _
        New FrameworkPropertyMetadata(False, New PropertyChangedCallback(AddressOf OnIsHiddenChanged)))

    Public Shared Sub SetIsHidden(ByVal element As UIElement, ByVal value As Boolean)
        element.SetValue(IsHiddenProperty, value)
    End Sub

    Public Shared Function GetIsHidden(ByVal element As UIElement) As Boolean
        Return DirectCast(element.GetValue(IsHiddenProperty), Boolean)
    End Function

    Private Shared Sub OnIsHiddenChanged(ByVal d As DependencyObject, ByVal e As DependencyPropertyChangedEventArgs)
        If System.ComponentModel.DesignerProperties.GetIsInDesignMode(d) AndAlso True.Equals(e.NewValue) Then
            With DirectCast(d, FrameworkElement)
                .Width = 0
                .Height = 0
            End With
        End If
    End Sub
End Class

声明命名空间后，可以按如下方式使用该功能：

<Grid ... local:DesignModeTool.IsHidden="True">
[stuff I don't want to be shown in the designer]
</Grid>

除了不使用设计器之外（真的，考虑一下这个），您可以将Grid的内容分离到一个单独的UserControl中，这样，您就可以独立于可见性逻辑更新那个UserControl。

我最近也遇到过类似的问题。
我正在使用一个Rectangle在模式对话框执行期间隐藏主窗口。我绑定了可见性数据，但是Rectangle使设计器无法使用。我将Z索引作为一次性数据绑定，并且回退值低于我想要隐藏的窗口。当应用程序启动时，Rectangle的Z索引被绑定到一个高于窗口的值。

我在另一边...讨厌VS 2012在设计器中隐藏隐藏WPF控件。我需要看到它们，所以我修改了gregsdennis代码：

public class DesignModeTool
{
    public static readonly DependencyProperty IsHiddenProperty = DependencyProperty.RegisterAttached("IsHidden",   typeof(bool),  typeof(DesignModeTool),   new FrameworkPropertyMetadata(false, new PropertyChangedCallback(OnIsHiddenChanged)));

    public static void SetIsHidden(FrameworkElement element, bool value)
    {
        element.SetValue(IsHiddenProperty, value);
    }

    public static bool GetIsHidden(FrameworkElement element)
    {
        return (bool)element.GetValue(IsHiddenProperty);
    }

    private static void OnIsHiddenChanged(DependencyObject d,
                                          DependencyPropertyChangedEventArgs e)
    {
        if (!DesignerProperties.GetIsInDesignMode(d)) return;
        var element = (FrameworkElement)d;
        element.Visibility=Visibility.Visible;

    }
}

wpfClasses2：DesignModeTool.IsHidden =“False”将在设计器模式下显示控件。

可能对其他人有用。如果你想在VS2022的设计器模式下隐藏元素：

d:Visibility="Hidden"